Cagrilinitide 10mg lyophilized powder

Cagrilinitide 10mg Lyophilized Research Peptide: Advanced Technical & Structural Profile

Product Overview

The Cagrilinitide 10mg lyophilized powder represents a specialized benchmark in long-acting amylin analogue synthesis, engineered specifically for advanced laboratory investigations, receptor binding assays, and metabolic pathway modeling. As a synthetic analogue of human amylin, this compound acts on calcitonin and amylin receptor complexes to support high-throughput in-vitro protocols. Distributed in a secure 10mg configuration, this pharmaceutical-grade lyophilized solid supports rigorous scientific studies requiring strict purity standards (>98\% verified via High-Performance Liquid Chromatography and Mass Spectrometry).

Structural Characteristics and Biochemical Properties

Molecular Formula: C194H312N54O59S2

Molecular Weight: 4,409.07 Da

CAS Number: 1415456-99-3 (also referenced as 2171674-71-6)

Amino Acid Count: 37-residue sequence featuring a specialized C-terminal modification and an attached fatty diacid side chain designed to enhance structural stability and serum albumin binding.

Appearance: White lyophilized solid cake, vacuum-sealed under an inert atmosphere to ensure maximum integrity.

Solubility: Compatible with standard aqueous bacteriostatic buffers for analytical titration.

Mechanism of Action in Experimental Models

In controlled research settings, the primary utility of Cagrilintide lies in its selective interaction profile across metabolic signaling pathways:

1 Amylin Receptor Agonism: Selectively binds to and activates amylin receptor complexes (such as CTR/RAMP combinations) to evaluate cellular signaling dynamics.

2 Satiety and Energy Balance Modeling: Utilized in-vitro to study central nervous system pathways related to energy homeostasis and metabolic regulation.

3 Receptor Interaction Studies: Acts as a reference standard for investigating combination-preparation protocols alongside incretin analogues in preclinical testing.

The integration of the lipid chain extends its kinetic profile, supporting extended-duration in-vitro and in-vivo pharmacokinetic modeling.

Quality Assurance, Handling, and Storage Protocol

Purity Verification: Each individual batch undergoes rigorous third-party analytical testing via HPLC and mass spectrometry, ensuring a verified purity threshold exceeding 98\% with complete documentation available via lot-specific Certificates of Analysis.

Lyophilized Storage: Store dry powder at -20^\circ\text{C} in a desiccated, dark environment protected from direct light and moisture exposure.

Reconstitution Guidelines: Reconstitute strictly using sterile bacteriostatic water, introducing the solvent gently down the inner glass wall to maintain structural integrity and avoid mechanical shearing.

Post-Reconstitution Maintenance: Store reconstituted solutions between 2•C and 8•C, utilizing contents within standard experimental stability windows.