Thymosin Alpha-1 10mg | Thymalfasin

Thymosin Alpha-1 10mg Lyophilized Research Peptide: Advanced Technical & Structural Profile

Product Overview

The Thymosin Alpha-1 10mg (Thymalfasin) lyophilized powder represents a peak benchmark in synthetic immunomodulatory peptide synthesis, engineered specifically for sophisticated laboratory investigations, cellular signaling assays, and immune response pathway modeling. As a synthetic 28-amino-acid, N-terminally acetylated polypeptide matching the naturally occurring thymic peptide, this reference material provides exceptional structural consistency for high-throughput in-vitro protocols. Distributed in a secure 10mg configuration, this pharmaceutical-grade lyophilized solid supports rigorous scientific studies requiring strict purity standards (\ge 99\% verified via High-Performance Liquid Chromatography and Mass Spectrometry).

Structural Characteristics and Biochemical Properties

Molecular Formula: C129H215N33O55

Molecular Weight: 3,108.30 Da

CAS Number: 62304-98-7

Amino Acid Sequence: Ac-Ser-Asp-Ala-Ala-Val-Asp-Thr-Ser-Ser-Glu-Ile-Thr-Thr-Lys-Asp-Leu-Lys-Glu-Lys-Lys-Glu-Val-Val-Glu-Glu-Ala-Glu-Asn (28-residue sequence featuring an N-terminal acetylation).

Appearance: White lyophilized solid cake, vacuum-sealed under an inert atmosphere to ensure maximum integrity.

Solubility: Fully soluble in aqueous solutions and compatible with standard bacteriostatic buffers for precise analytical titration.

Mechanism of Action in Experimental Models

In controlled research settings, the primary utility of Thymosin Alpha-1 lies in its targeted interaction profile across immune-modulating signaling networks:

1 Immune Cell Modulation: Interacts with Toll-like receptors (TLRs) and various signaling cascades to evaluate dendritic cell maturation and T-cell activation dynamics in-vitro.

2 Cytokine Pathway Regulation: Utilized in cellular assays to investigate the modulation of interferon production, interleukin expression, and inflammatory mediator signaling.

3 Receptor and Protein-Protein Interaction Assays: Acts as a stable reference standard for evaluating cellular defense mechanisms, immune reconstitution parameters, and thymic hormone pathways.

Quality Assurance, Handling, and Storage Protocol

Purity Verification: Each individual batch undergoes rigorous third-party analytical testing via HPLC and mass spectrometry, ensuring a verified purity threshold exceeding 99\% with complete documentation available via lot-specific Certificates of Analysis.

Lyophilized Storage: Store dry powder at -20^\circ\text{C} in a desiccated, dark environment protected from direct light, moisture exposure, and oxidative stress.

Reconstitution Guidelines: Reconstitute strictly using sterile bacteriostatic water, introducing the solvent gently down the inner glass wall to maintain structural integrity and avoid mechanical shearing.

Post-Reconstitution Maintenance: Store reconstituted solutions between 2•C and 8•C, utilizing contents within standard experimental stability windows.

Regulatory Notice: This material is supplied strictly for laboratory research, analytical reference, and scientific evaluation purposes only. It is explicitly not approved for human consumption, clinical diagnostic application, veterinary use, or therapeutic administration.